Our software products are based on the design concepts introduced in:

Chao, J., Ward, E. S., and Ober, R. J. A software framework for the analysis of complex microscopy image data. IEEE Transactions on Information Technology in Biomedicine, 14: 1075-1087, 2010

The algorithms that underlie a number of our modules are analyzed here:

Chao, J., Ram, S., Ward, E. S., and Ober, R. J. Ultrahigh accuracy imaging modality for super-localization microscopy Nature Methods, 10(4): 335-338, 2013.

Abraham, A. V., Ram, S., Chao, J., Ward, E. S., and Ober, R. J. Quantitative study of single molecule location estimation techniques. Optics Express, 17: 23352-23373, 2009.

Information theoretic approaches to the characterization of imaging experiments are presented in:

Ober, R. J., Ram, S., and Ward, E. S. Localization accuracy in single-molecule microscopy.Biophysical Journal, 86: 1185-1200, 2004.

Ram, S., Ward, E. S., and Ober, R. J. A stochastic analysis of performance limits for optical microscopes. Multidimensional Systems and Signal Processing, 17:27-57, 2006.